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Histopathologic & Mechanistic Assessment of Angiogenesis Inhibitor Related Toxicities: An EU FP7 Industry-Academia Partnerships & Pathways (IAPP) Funded Project


About AngioTox

AngioTox is an EU FP7-funded IAPP project integrating expertise in biomarker discovery, histopathology, multi-modality in vivo imaging and automated image analysis. 

The AngioTox Consortium was established in 2010 to mechanistically assess the toxicities associated with the use of angiogenesis inhibitors for the treatment of cancer. The ultimate goal of this consortium is to identify an AngioTox Safety Panel of toxicologic markers to facilitate improved screening of angiogenesis inhibitor toxicologic parameters, inform clinical drug dosing regimens, facilitate the development of more specific and potent angiogenesis inhibitors and significantly improve patient care. 

Consortium Members

Dr. Annette Byrne (Co-ordinator)
(Royal College of Surgeons in Ireland, Ireland)


Henk M.W Verheul, M.D. Ph.D., Professor of Medical Oncology (Scientific Coordinator)
VU University Medical Centre -VUmc Cancer Center Amsterdam

University College Dublin (Ireland)

F.Hoffman La-Roche (Switzerland), Genentech Inc. (USA)

OncoMark Ltd. (Ireland)

Pathology Experts (Switzerland)

Bayer Technology Services GmbH (Germany)

Latest News and Events

EMIM 2014
(For more on this see section 'News & Events' )

March 2014, AngioTox Outreach Activities
Marie Curie Fellows promoting Scientific Research....
(For more on this see section 'News & Events' )

March 2014, Amsterdam
Genentech sponsored AngioTox Symposium to be held in March
(For more on this see section 'News & Events' )

May 2013, Amsterdam
The AngioTox Consortium met in Amsterdam to hold a very successful Year 3 Meeting

October 2012, San Diego

AngioTox Coordinator presents to International Angiogenesis Research Community
(For more on this see section 'News & Events' )

June 2012: AngioTox Consortium meets in Dublin for Year 2 Planning Meeting and for Mid Term Review Meeting (For more on this see section 'News & Events' )

February 2012: AngioTox Fellow presents poster at International Symposium on Anti-Angiogenic Therapy: Recent Advances and Future Directions conference in La Jolla, San Diego, California (For more on this see section 'News & Events' )